LH response to GnRH blood test
定义
LH response to GnRH is a blood test to help determine if your pituitary gland can correctly respond to gonadotropin releasing hormone (GnRH). LH stands for luteinizing hormone.
选择的名字
Luteinizing hormone response to gonadotropin-releasing hormone
How the Test is Performed
A
How to Prepare for the Test
No special preparation is necessary.
How the Test will Feel
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. 这很快就会消失.
Why the Test is Performed
GnRH is a hormone made by the hypothalamus gland. LH is made by the pituitary gland. GnRH causes (stimulates) the pituitary gland to release LH.
This test is used to tell the difference between primary and secondary
Depending on the type of 性腺机能减退:
- Primary 性腺机能减退 starts in the testicle or ovary
- Secondary 性腺机能减退 starts in the hypothalamus or pituitary gland
This test may also be done to check:
- 低
睾酮 男性水平 - 低
雌二醇 女性水平
正常的结果
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your health care provider about the meaning of your specific test results.
What Abnormal Results Mean
An increased LH response suggests a problem in the ovaries or testes.
A reduced LH response suggests a problem with the hypothalamus gland or pituitary gland.
Abnormal results may also be due to:
- Pituitary gland problems, such as release of too much hormone (
高泌乳素血症 ) - 大
垂体肿瘤 - Decrease in hormones made by the
内分泌腺 - Too much iron in the body (
血色沉着病 ) - Eating disorders, such as
厌食症 - Recent significant weight loss, such as after bariatric surgery
- Delayed or absent puberty (Kallmann syndrome)
- Lack of periods in women (
闭经 ) - 肥胖
风险
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks related to having blood drawn are slight, but may include:
- 大出血
- Fainting or feeling lightheaded
- Multiple punctures to locate veins
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
参考文献
Guber HA, Oprea M, Russell YX. Evaluation of endocrine function. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24日艾德. Philadelphia, PA: Elsevier; 2022:chap 25.
凯泽,何凯. Pituitary physiology and diagnostic evaluation. In: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14日艾德. Philadelphia, PA: Elsevier; 2020:chap 8.
审核日期: 07/13/2021
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